Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20227221 | 0.87 | NOTUM (0.38) | ALDH1A1HPGD | |
| SCHEMBL23397289 | 0.86 | ACACB (0.36) | BCHEECE1HPGD | |
| SCHEMBL20224080 | 0.86 | ECE1 (0.31) | BCHEECE1 | |
| SCHEMBL18052988 | 0.76 | PTGER4 (0.35) | — | |
| SCHEMBL18054225 | 0.74 | BCHE (0.34) | BCHEALDH1A1HPGDSMN1; SMN2P2RX4 | |
| SCHEMBL18054201 | 0.73 | CYP19A1 (0.37) | — | |
| SCHEMBL18052992 | 0.72 | ACHE (0.37) | BCHEALDH1A1HPGDSMN1; SMN2P2RX4 | |
| SCHEMBL20224068 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL18054255 | 0.71 | NOTUM (0.41) | ALDH1A1HPGD | |
| SCHEMBL23397291 | 0.71 | PTGS2 (0.33) | BCHEALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016138527-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE, INC. (US) | 2016-09-01 | — | — | WO | disclosed |