Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735158 | 0.92 | TRPA1 (0.39) | KDM4EALOX15TRPA1BLMPMP22 | |
| SCHEMBL19546089 | 0.88 | BLM (0.41) | KDM4EMAPTALOX15SMN1; SMN2TRPA1 | |
| SCHEMBL12779671 | 0.85 | ALOX15 (0.50) | KDM4EMAPTALOX15SMN1; SMN2TRPA1 | |
| SCHEMBL21427999 | 0.84 | CYP2D6 (0.37) | SMN1; SMN2TRPA1BLMPMP22HSD17B10 | |
| SCHEMBL14012821 | 0.84 | BLM (0.50) | KDM4EMAPTALOX15SMN1; SMN2BLM | |
| SCHEMBL22821372 | 0.81 | ALDH1A1 (0.41) | KDM4EMAPTALOX15SMN1; SMN2TRPA1 | |
| SCHEMBL19545889 | 0.81 | CYP2D6 (0.41) | CYP2D6 | |
| SCHEMBL8571 | 0.80 | MAPT (0.36) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL5345639 | 0.80 | MAPT (0.36) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL18412665 | 0.80 | BLM (0.55) | KDM4EALOX15SMN1; SMN2BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251470-A1 | ZWITTERIONIC POLYSACCHARIDE POLYMERS HAVING ANTIFOULING, ANTIMICROBIAL AND OPTICAL TRANSPARENCY PROPERTIES | NATIONAL SCIENCE FOUNDATION | 2016-09-01 | — | — | US | disclosed |