SCHEMBL18057043

SCHEMBL18057043

CC(=O)COCC(=O)NCCCCCCNC(=O)COCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 1/20 0.49
▸ ADRA1A P35348 1/20 0.43
▸ CYP2C19 P33261 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ EPHX2 P34913 1/20 0.40
▸ GLP1R P43220 5/20 0.39
▸ CES2 O00748 1/20 0.39
▸ CASP2 P42575 1/20 0.39
▸ NAMPT P43490 1/20 0.39
▸ PRMT1 Q99873 1/20 0.37
▸ NAAA Q02083 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11908564 0.91 ALDH1A1 (0.48) FAAHADRA1ACYP2C19KDM4EMAPK1
SCHEMBL15552174 0.91 ALDH1A1 (0.48) FAAHADRA1ACYP2C19KDM4EMAPK1
SCHEMBL9356724 0.89 MEN1 (0.44) FAAHADRA1ACYP2C19MEN1KMT2A
SCHEMBL13411276 0.87 FAAH (0.47) FAAHKDM4EMAPK1HIF1AMEN1
SCHEMBL24622918 0.86 FAAH (0.62) FAAHEPHX2GLP1RCASP2NAAA
SCHEMBL17817086 0.86 FAAH (0.62) FAAHEPHX2GLP1RCASP2NAAA
SCHEMBL17817084 0.86 FAAH (0.62) FAAHEPHX2GLP1RCASP2NAAA
SCHEMBL15613427 0.86 FAAH (0.62) FAAHEPHX2GLP1RCASP2NAAA
SCHEMBL11362980 0.84 TDP1 (0.43) FAAHCYP2C19MEN1KMT2AALDH1A1
SCHEMBL10140852 0.84 FAAH (0.59) FAAHMEN1KMT2AEPHX2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 FAAH 1119/4885ADRA1A 2283/4885CYP2C19 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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