Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694863 | 0.89 | GSK3B (0.39) | S100A4EP300KAT2BRAD51 | |
| SCHEMBL18058748 | 0.89 | GSK3B (0.39) | S100A4EP300KAT2BRAD51 | |
| SCHEMBL18058838 | 0.88 | MEN1 (0.36) | S100A4EP300KAT2BRAD51MEN1 | |
| SCHEMBL15731795 | 0.83 | PIK3R1 (0.39) | EP300KAT2BRAD51MEN1KMT2A | |
| SCHEMBL6330031 | 0.82 | KMT2A (0.49) | RAD51MEN1KMT2AMAPTHTT | |
| SCHEMBL29483984 | 0.82 | RAD51 (0.51) | RAD51MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17576245 | 0.82 | AKR1C3 (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL1919863 | 0.82 | AKR1C3 (0.44) | EP300KAT2BRAD51MEN1KMT2A | |
| SCHEMBL20050092 | 0.82 | ALDH1A1 (0.42) | EP300KAT2BMEN1KMT2AMAPT | |
| SCHEMBL186752 | 0.82 | LMNA (0.51) | RAD51MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3064497-A1 | DIMER IMPURITIES OF APIXABAN AND METHOD TO REMOVE THEM | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2016-09-07 | — | — | EP | disclosed |