Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731795 | 0.87 | PIK3R1 (0.39) | ALDH1A1MAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL5444324 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4ETSHRL3MBTL1 | |
| SCHEMBL6330031 | 0.86 | KMT2A (0.49) | ALDH1A1MAPTSMN1; SMN2LMNATDP1 | |
| SCHEMBL29483984 | 0.86 | RAD51 (0.51) | MAPTSMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL1919863 | 0.86 | AKR1C3 (0.44) | ALDH1A1MAPTSMN1; SMN2MEN1HTT | |
| SCHEMBL17576245 | 0.86 | AKR1C3 (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL186752 | 0.85 | LMNA (0.51) | ALDH1A1MAPTSMN1; SMN2LMNATDP1 | |
| SCHEMBL16730262 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL20694863 | 0.84 | GSK3B (0.39) | EP300KAT2B | |
| SCHEMBL18028120 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099963-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | UNICHEM LAB LTD (IN) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099963-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | HAX1, CYP4X1, HTRA1 | ALDH1A1 490/4885MAPT 4264/4885SMN1; SMN2 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.