Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731795 | 0.87 | PIK3R1 (0.39) | RAD51MAPTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL20050092 | 0.86 | ALDH1A1 (0.42) | MAPTSMN1; SMN2TSHRPRKDCTDP1 | |
| SCHEMBL17576245 | 0.86 | AKR1C3 (0.44) | MAPTSMN1; SMN2AKR1C3TDP1MEN1 | |
| SCHEMBL1919863 | 0.86 | AKR1C3 (0.44) | RAD51MAPTSMN1; SMN2AKR1C3MEN1 | |
| SCHEMBL6330031 | 0.86 | KMT2A (0.49) | RAD51MAPTSMN1; SMN2AKR1C3PRKDC | |
| SCHEMBL186752 | 0.85 | LMNA (0.51) | RAD51MAPTSMN1; SMN2AKR1C3TSHR | |
| SCHEMBL18028120 | 0.84 | ALDH1A1 (0.42) | RAD51MAPTSMN1; SMN2TSHRPTGS2 | |
| SCHEMBL18058760 | 0.84 | PTGS2 (0.41) | MAPTSMN1; SMN2TDP1PTGS2MEN1 | |
| SCHEMBL20694863 | 0.84 | GSK3B (0.39) | RAD51 | |
| SCHEMBL18058748 | 0.84 | GSK3B (0.39) | RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143914-B | Preparation method of apixaban intermediate | 常州恒邦药业有限公司 | 2022-03-29 | — | — | CN | disclosed |