Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546413 | 0.80 | CYP3A4 (0.52) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15924824 | 0.75 | CYP2D6 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL15924491 | 0.74 | CYP2D6 (0.45) | CYP3A4CYP2D6KMT2AMEN1ALDH1A1 | |
| SCHEMBL11301180 | 0.74 | CYP3A4 (0.53) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23043010 | 0.72 | MEN1 (0.47) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1554888 | 0.71 | KDM4E (0.44) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28225504 | 0.70 | CYP2D6 (0.43) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL567927 | 0.70 | KDM4E (0.63) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20502739 | 0.70 | KDM4E (0.63) | KDM4EGAACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL567928 | 0.70 | KDM4E (0.63) | KDM4EGAACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | claimed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | claimed |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2019-06-06 | — | — | US | disclosed |
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2019-02-19 | — | — | US | disclosed |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | disclosed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | TEC, ETFA, TECR | KDM4E 3191/4885GAA 2931/4885CYP3A4 129/4885 |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, GTF2I, POF1B | KDM4E 4599/4885GAA 4791/4885CYP3A4 640/4885 |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | TEC, ETFA, TECR | KDM4E 3191/4885GAA 2931/4885CYP3A4 129/4885 |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, COG7, COG4 | KDM4E 4489/4885GAA 3658/4885CYP3A4 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.