Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548305 | 0.85 | TSHR (0.62) | TSHRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL1139007 | 0.84 | MMP12 (0.60) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL10521027 | 0.84 | MMP12 (0.60) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL13946243 | 0.84 | CYP1A2 (0.67) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5743507 | 0.83 | TSHR (0.56) | TSHRCYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27583120 | 0.82 | ALDH1A1 (0.65) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5661624 | 0.81 | TSHR (0.61) | TSHRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL3097653 | 0.81 | TSHR (0.61) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2561037 | 0.80 | TSHR (0.56) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4799370 | 0.80 | MMP2 (0.55) | TSHRANPEPERAP2ERAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770711-B2 | General catalyst for C-H functionalization | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-26 | — | — | US | disclosed |
| US-20160272662-A1 | GENERAL CATALYST FOR C-H FUNCTIONALIZATION | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272662-A1 | GENERAL CATALYST FOR C-H FUNCTIONALIZATION | BET1, PLEC, NUDC | TSHR 2007/4885MEN1 133/4885KMT2A 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.