Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NQO2 | P16083 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL28338134 | 0.88 | ALDH1A1 (0.58) | MAPTNQO2NPC1KMT2APOLB | |
| Naphthalene SCHEMBL303703 | 0.86 | CYP2A6 (0.40) | ALDH1A1EGFR | |
| Quinoxaline SCHEMBL1088189 | 0.84 | ALDH1A1 (0.38) | MAPTNPC1KMT2AMEN1USP2 | |
| Phenanthrene SCHEMBL984028 | 0.83 | CYP2A6 (0.50) | MAPTNQO2ALDH1A1HSD17B10TDP1 | |
| Quinoline SCHEMBL2443761 | 0.82 | ALDH1A1 (0.63) | MAPTNPC1KMT2AMEN1POLB | |
| Quinoline SCHEMBL27783840 | 0.82 | ALDH1A1 (0.63) | MAPTNPC1KMT2AMEN1POLB | |
| Anthracene SCHEMBL27585398 | 0.82 | ALDH1A1 (0.37) | MAPTNQO2ALDH1A1HPGDHSD17B10 | |
| Hydrochlorthiazide SCHEMBL4422849 | 0.82 | KDM4E (0.32) | MAPTNPC1ALDH1A1HPGDKDM4E | |
| Quinoline SCHEMBL28958673 | 0.81 | ALDH1A1 (0.61) | MAPTNPC1KMT2AMEN1POLB | |
| Quinoline SCHEMBL27516885 | 0.81 | ALDH1A1 (0.61) | MAPTNPC1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272750-A1 | NOVEL IMPACT MODIFIERS FOR EPOXY-BASED ADHESIVES | SIKA TECHNOLOGY AG (CH) | 2016-09-22 | — | — | US | disclosed |