Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL3934202 | 0.91 | TSHR (0.38) | CYP2A6ALOX12CYP19A1CYP11B1CYP11B2 | |
| Anthracene SCHEMBL27585398 | 0.91 | ALDH1A1 (0.37) | CYP2A6ALOX12EGFRCYP19A1CYP11B1 | |
| Isoquinoline SCHEMBL1743732 | 0.88 | TNF (0.37) | CYP2A6EGFRCYP19A1CYP11B1CYP11B2 | |
| Isoquinoline SCHEMBL29501078 | 0.88 | TNF (0.37) | CYP2A6EGFRCYP19A1CYP11B1CYP11B2 | |
| Phenanthrene SCHEMBL984028 | 0.87 | CYP2A6 (0.50) | CYP2A6ALDH1A1 | |
| Phenazine SCHEMBL18063602 | 0.86 | MAPT (0.50) | EGFRALDH1A1 | |
| Pyrene SCHEMBL17144401 | 0.84 | HSD17B10 (0.48) | ALDH1A1 | |
| Acridine SCHEMBL28338134 | 0.83 | ALDH1A1 (0.58) | CYP2A6EGFRALDH1A1 | |
| Hydrochlorthiazide SCHEMBL29221322 | 0.83 | NQO2 (0.38) | CYP2A6CYP19A1CYP11B1CYP11B2CYP17A1 | |
| Hydrochlorthiazide SCHEMBL9218829 | 0.83 | CYP2A6 (0.59) | CYP2A6CYP19A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702546-B2 | Near-infrared heptamethine dyes for generation of singlet oxygen | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-07-18 | — | — | US | claimed |
| US-20230173071-A1 | TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT | CALIFORNIA INST OF TECHN (US) | 2023-06-08 | — | — | US | claimed |
| CN-113286788-A | Treatment of myopia and other eye disorders using singlet oxygen | 加州理工学院 | 2021-08-20 | — | — | CN | claimed |
| CN-109602907-B | Silica nanoparticle drug carrier, diagnosis and treatment preparation and preparation method thereof | 北京大学 | 2020-05-05 | — | — | CN | claimed |
| US-20200129620-A1 | Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-04-30 | — | — | US | claimed |
| US-20200131370-A1 | Near-Infrared Heptamethine Dyes For Generation Of Singlet Oxygen | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-04-30 | — | — | US | claimed |
| EP-1609459-B1 | Use of polycationic compounds for dyeing keratinous fibers | OREAL (FR) | 2009-04-08 | — | — | EP | claimed |
| EP-1354919-B1 | LATENT IMAGE-USE PRINTING INK COMPOSITION, PRINTED MATTER CONTAINING LATENT IMAGE RECORDED BY THE INK COMPOSITION, READING METHOD BY LATENT IMAGE INFORMATION AND LATENT IMAGE INFORMATION READING DEVICE | FUJITSU LTD (JP) | 2008-08-13 | — | — | EP | claimed |
| JP-2008510698-A | — | — | 2008-04-10 | — | — | JP | claimed |
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |
| US-4536473-A | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-08-20 | — | — | US | claimed |
| EP-0138543-A2 | Silver halide photographic light sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-24 | — | — | EP | claimed |
| EP-0132165-A1 | Adsorbable alkynyl substituted heterocyclic quaternary ammonium salts and applications thereof to silver halide photography | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-01-23 | — | — | EP | claimed |
| EP-0123983-A2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-07 | — | — | EP | claimed |
| US-4471044-A | Silver halide emulsions and photographic elements containing adsorbable alkynyl substituted heterocyclic quaternary ammonium salts | EASTMAN KODAK COMPANY (US) | 1984-09-11 | — | — | US | claimed |
| US-4463087-A | Controlled site epitaxial sensitization of limited iodide silver halide emulsions | EASTMAN KODAK COMPANY (US) | 1984-07-31 | — | — | US | claimed |
| US-4435501-A | SILVER HALIDE EMULSIONS | EASTMAN KODAK COMPANY (US) | 1984-03-06 | — | — | US | claimed |
| US-4425426-A | SENSITIZING DYE ADSORBED TO SILVER HALIDE GRAINS | EASTMAN KODAK COMPANY (US) | 1984-01-10 | — | — | US | claimed |
| US-4425425-A | SENSITIZERS, SILVER HALIDE EMULSIONS | EASTMAN KODAK COMPANY (US) | 1984-01-10 | — | — | US | claimed |
| US-4289693-A | TEXTILES | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129620-A1 | Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light | CRY1, MYH10, MYLK | CYP2A6 2287/4885ALOX12 258/4885EGFR 4271/4885 |
| US-20230173071-A1 | TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT | CRY1, MYH10, MYLK | CYP2A6 2287/4885ALOX12 258/4885EGFR 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.