Acridine

Acridine

SCHEMBL28338134

c1ccc2nc3ccccc3cc2c1.c1cscn1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
HPGD P15428 3/20 0.58
GLA P06280 2/20 0.58
MAPT P10636 2/20 0.58
ACHE P22303 1/20 0.58
HTR3A P46098 1/20 0.44
NQO2 P16083 1/20 0.40
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
PTBP1 P26599 1/20 0.39
RCE1 Q9Y256 1/20 0.39
PDGFRB P09619 2/20 0.38
PDGFRA P16234 2/20 0.38
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL27585398 0.88 ALDH1A1 (0.37) ALDH1A1HPGDGLAMAPTACHE
Phenazine SCHEMBL18063602 0.88 MAPT (0.50) ALDH1A1HPGDGLAMAPTACHE
Naphthalene SCHEMBL303703 0.83 CYP2A6 (0.40) ALDH1A1EGFRCYP2A6
Quinoline SCHEMBL27783840 0.79 ALDH1A1 (0.63) ALDH1A1MAPTRAB9ANPC1KDM4E
Quinoline SCHEMBL2443761 0.79 ALDH1A1 (0.63) ALDH1A1MAPTRAB9ANPC1KDM4E
Hydrochlorthiazide SCHEMBL28012369 0.79 RAB9A (0.39) ALDH1A1HPGDGLAMAPTACHE
Hydrochlorthiazide SCHEMBL27966523 0.79 BACE1 (0.63) ALDH1A1HPGDMAPTHTR3ARAB9A
Quinoline SCHEMBL28958673 0.78 ALDH1A1 (0.61) ALDH1A1MAPTRAB9ANPC1KDM4E
Quinoxaline SCHEMBL1088189 0.78 ALDH1A1 (0.38) ALDH1A1HPGDMAPTRAB9ANPC1
Acridine SCHEMBL28156525 0.77 ALDH1A1 (0.71) ALDH1A1HPGDGLAMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563938-A Polyether copolymer, crosslinkable polyether copolymer composition, electrolyte, and composite 日本瑞翁株式会社 2019-12-13 CN disclosed