Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.53 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863984 | 0.91 | PTPN1 (0.51) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL18065719 | 0.88 | NPC1 (0.58) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL18085423 | 0.79 | L3MBTL1 (0.50) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL10736480 | 0.79 | SLC13A5 (0.49) | MEN1KMT2AALDH1A1PTPN1LMNA | |
| SCHEMBL16892959 | 0.78 | F2RL1 (0.53) | TAAR1ALDH1A1F2RL1ALOX5 | |
| SCHEMBL3266754 | 0.77 | PTPRB (0.71) | GAAF2RL1PTPN1 | |
| SCHEMBL2355634 | 0.76 | LTA4H (0.75) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL24800806 | 0.76 | F2RL1 (0.74) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL3971720 | 0.76 | HDAC3 (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9767865 | 0.74 | KCNN4 (0.46) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950993-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-04-24 | — | — | US | disclosed |
| US-9950993-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160271081-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160271081-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271081-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | MEN1 4227/4885KMT2A 4731/4885ATM 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.