Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12782048 | 0.85 | LMNA (0.42) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL1767736 | 0.83 | MAPT (0.47) | L3MBTL1MEN1KMT2AEGFRLCK | |
| SCHEMBL12290810 | 0.82 | MAPT (0.37) | L3MBTL1MEN1KMT2ALMNAPOLB | |
| SCHEMBL26290 | 0.79 | ALOX15 (0.40) | — | |
| SCHEMBL182606 | 0.79 | KMT2A (0.41) | KMT2ALMNAALDH1A1GAARAB9A | |
| SCHEMBL1199479 | 0.77 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ALMNAPOLB | |
| SCHEMBL1539284 | 0.77 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ANQO1LMNA | |
| SCHEMBL9114461 | 0.76 | NQO1 (0.64) | L3MBTL1MEN1KMT2ANQO1LMNA | |
| SCHEMBL4090032 | 0.76 | AKR1C3 (0.45) | L3MBTL1MEN1KMT2ALMNAGAA | |
| SCHEMBL15748700 | 0.75 | MAPK1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |