SCHEMBL1806887

SCHEMBL1806887

O=Cc1ccc(C=O)c(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.47
BLM P54132 1/20 0.47
KMT2A Q03164 1/20 0.47
ERN1 O75460 3/20 0.42
KCNJ1 P48048 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
TSHR P16473 1/20 0.38
TYR P14679 2/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31306389 1.00 TDP1 (0.47) TDP1MEN1LMNATHRBBLM
SCHEMBL31306390 1.00 TDP1 (0.47) TDP1MEN1LMNATHRBBLM
SCHEMBL745181 0.89 ERN1 (0.46) TDP1MEN1LMNATHRBBLM
SCHEMBL17842843 0.84 TDP1 (0.46) TDP1MEN1LMNATHRBBLM
SCHEMBL154414 0.84 ALDH1A1 (0.44) TDP1MEN1LMNATHRBBLM
SCHEMBL23462843 0.84 TDP1 (0.36) TDP1MEN1LMNATHRBBLM
SCHEMBL5094577 0.84 TDP1 (0.36) TDP1MEN1LMNATHRBBLM
SCHEMBL219001 0.84 TRIM24 (0.44) MEN1KMT2AERN1TRIM24TRIM33
SCHEMBL898807 0.84 TDP1 (0.36) TDP1MEN1LMNATHRBBLM
SCHEMBL6853865 0.81 KMT2A (0.58) TDP1MEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118892818-B Solid caking drying agent and preparation method thereof 佛山市顺德区特普高实业有限公司 2024-12-13 CN claimed
CN-118892818-A Solid caking drying agent and preparation method thereof 佛山市顺德区特普高实业有限公司 2024-11-05 CN claimed
CN-102659545-A Novel liquid crystal intermediate 2,3-difluoro terephthalaldehyde JIANGSU TETRACHEM CO LTD 2012-09-12 CN claimed
CN-118892818-B Solid caking drying agent and preparation method thereof 佛山市顺德区特普高实业有限公司 2024-12-13 CN disclosed
CN-118892818-A Solid caking drying agent and preparation method thereof 佛山市顺德区特普高实业有限公司 2024-11-05 CN disclosed
US-20230330604-A1 MOLECULARLY POROUS CROSS-LINKED MEMBRANES UNIV KING ABDULLAH SCI & TECH (SA) 2023-10-19 US disclosed
WO-2022058961-A1 MOLECULARLY POROUS CROSS-LINKED MEMBRANES KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-03-24 WO disclosed
CN-102659545-A Novel liquid crystal intermediate 2,3-difluoro terephthalaldehyde JIANGSU TETRACHEM CO LTD 2012-09-12 CN disclosed
CN-102659545-A Novel liquid crystal intermediate 2,3-difluoro terephthalaldehyde JIANGSU TETRACHEM CO LTD 2012-09-12 CN disclosed
CN-102659545-A Novel liquid crystal intermediate 2,3-difluoro terephthalaldehyde JIANGSU TETRACHEM CO LTD 2012-09-12 CN disclosed
US-7939695-B2 Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO K.K. (JP) 2011-05-10 US disclosed
US-20100145106-A1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2010-06-10 US disclosed
US-7540991-B2 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. (JP) 2009-06-02 US disclosed
EP-1915331-A2 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL Showa Denko K.K. (JP) 2008-04-30 EP disclosed
EP-1615286-B1 Ion conductive polymer electrolyte membrane and production method for the same POLYMATECH CO LTD (JP) 2007-09-12 EP disclosed
WO-2006137348-A2 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2006-12-28 WO disclosed
EP-1615286-A1 Ion conductive polymer electrolyte membrane and production method for the same Polymatech Co., Ltd. (JP) 2006-01-11 EP disclosed
US-20060004112-A1 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145106-A1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL NPM1, MED1, KPNA2 TDP1 3007/4885MEN1 110/4885LMNA 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.