Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18070912 | 0.78 | KDM4E (0.47) | PLAUMAPTKDM4ERPS6KB1AURKA | |
| SCHEMBL15528783 | 0.74 | KMT2A (0.56) | MAPTKDM4ERPS6KB1AURKAALDH1A1 | |
| SCHEMBL15529175 | 0.73 | MAPT (0.57) | MAPTKDM4ERPS6KB1AURKAALDH1A1 | |
| SCHEMBL18048981 | 0.68 | KDR (0.56) | MAPTKDM4ERPS6KB1AURKAPDPK1 | |
| SCHEMBL18048969 | 0.67 | VNN1 (0.51) | PLAUMAPTKDM4EPDPK1ALDH1A1 | |
| SCHEMBL18070922 | 0.66 | KDM4E (0.62) | MAPTKDM4ERPS6KB1AURKAPDPK1 | |
| SCHEMBL18048963 | 0.65 | L3MBTL1 (0.53) | MAPTALDH1A1VNN1KMT2A | |
| SCHEMBL26923596 | 0.65 | CYP2C9 (0.49) | KDM4EALDH1A1HPGDVNN1KMT2A | |
| SCHEMBL18049798 | 0.65 | VNN1 (0.46) | MAPTALDH1A1HPGDVNN1KMT2A | |
| SCHEMBL18048975 | 0.65 | NAMPT (0.47) | MAPTRPS6KB1AURKAPDPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |