SCHEMBL18071768

SCHEMBL18071768

O=C(C#Cc1ccc2c3c(cccc13)C(=O)N(OS(=O)(=O)C(F)(F)F)C2=O)OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.42
▸ KMT2A Q03164 4/20 0.42
▸ POLB P06746 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ ALDH1A1 P00352 8/20 0.34
▸ KDM4E B2RXH2 7/20 0.34
▸ HPGD P15428 5/20 0.34
▸ HTT P42858 2/20 0.34
▸ GAA P10253 1/20 0.31
▸ APOBEC3A P31941 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ CASP6 P55212 1/20 0.31
▸ APOBEC3G Q9HC16 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ LMNA P02545 2/20 0.30
▸ THRB P10828 1/20 0.30
▸ PABPC1 P11940 1/20 0.30
▸ XBP1 P17861 1/20 0.30
▸ NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18069164 0.90 MAPT (0.41) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18069161 0.86 KMT2A (0.42) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL19015151 0.83 POLB (0.33) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18069159 0.82 MAPT (0.39) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18069220 0.82 KMT2A (0.39) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18069169 0.81 MEN1 (0.41) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL17185507 0.80 KMT2A (0.45) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18071767 0.80 MEN1 (0.38) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL18069172 0.79 MAPT (0.40) MAPTKMT2APOLBMEN1L3MBTL1
SCHEMBL12296926 0.79 KMT2A (0.40) MAPTKMT2APOLBMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220026801-A1 CHEMICALLY AMPLIFIED POSITIVE -TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, AND METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD (JP) 2022-01-27 — — US disclosed
US-20200209748-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, AND METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2020-07-02 — — US disclosed
US-9709886-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2017-07-18 — — US disclosed
EP-3182203-A1 A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS Heraeus Precious Metals North America Daychem LLC (US) 2017-06-21 — — EP disclosed
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2017-01-05 — — US disclosed
US-9477150-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-10-25 — — US disclosed
WO-2016148809-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS Heraeus Precious Metals North America Daychem LLC (US) 2016-09-22 — — WO disclosed
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 MAPT 3437/4885KMT2A 1020/4885POLB 840/4885
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 MAPT 3437/4885KMT2A 1020/4885POLB 840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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