Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050232 | 0.84 | AGPAT2 (0.40) | EPHX2SCN4AAGPAT2HRH4KIF11 | |
| SCHEMBL18050298 | 0.82 | AGPAT2 (0.39) | AGPAT2HRH4PIK3CAPIK3CBPIK3CG | |
| SCHEMBL18072963 | 0.73 | ALDH1A1 (0.32) | EPHX2SCN4AAGPAT2HRH4KIF11 | |
| SCHEMBL8058929 | 0.72 | KDM4E (0.50) | KDM4EHSD17B10NPC1ALDH1A1MAPT | |
| SCHEMBL19299836 | 0.72 | AGPAT2 (0.31) | AGPAT2HRH4PIK3CAPIK3CBPIK3CG | |
| SCHEMBL18050222 | 0.72 | S1PR1 (0.34) | AGPAT2ALDH1A1HPGD | |
| SCHEMBL167098 | 0.71 | MEN1 (0.57) | AGPAT2KIF11KDM4EHSD17B10NPC1 | |
| SCHEMBL10281012 | 0.71 | HSD11B1 (0.52) | AGPAT2KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11180476 | 0.71 | KIF11 (0.47) | AGPAT2KIF11KDM4EHSD17B10PIK3CA | |
| SCHEMBL13811129 | 0.71 | KIF11 (0.42) | EPHX2SCN4AKIF11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016142327-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | WO | disclosed |