Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 1.00 |
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | TNF | P01375 | 1/20 | 1.00 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 1.00 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290351 | 0.86 | CA12 (0.80) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL28336577 | 0.85 | CA12 (0.74) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL30468190 | 0.85 | CA12 (0.74) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL29178472 | 0.85 | CA12 (0.74) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL1181304 | 0.85 | CA12 (0.74) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL26804772 | 0.83 | POLB (1.00) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL10629604 | 0.82 | CA12 (0.70) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL18073946 | 0.82 | CA12 (0.70) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL12722537 | 0.82 | CA12 (0.70) | CA12CA9TNFNOD2NOD1 | |
| SCHEMBL28138386 | 0.82 | ALDH1A1 (0.76) | CA12CA9TNFNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117590694-A | Photosensitive resin composition, photosensitive resist laminate and application thereof | 杭州福斯特电子材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-3268372-B9 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| CN-107548397-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-12-29 | — | — | CN | disclosed |
| US-20200377514-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-12-03 | — | — | US | disclosed |
| US-10822345-B2 | KV1.3 inhibitors and their medical application | 4SC AG (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20200339592-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-10-29 | — | — | US | disclosed |
| US-10723743-B2 | Kv1.3 inhibitors and their medical application | 4SC AG (DE) | 2020-07-28 | — | — | US | disclosed |
| US-10703735-B2 | 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer | LEAD DISCOVERY CENTER GMBH (DE) | 2020-07-07 | — | — | US | disclosed |
| US-10703735-B2 | 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer | LEAD DISCOVERY CENTER GMBH (DE) | 2020-07-07 | — | — | US | disclosed |
| EP-3268372-B1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10399991-B2 | Kv1.3 inhibitors and their medical applications | 4SC AG (DE) | 2019-09-03 | — | — | US | disclosed |
| US-20190185483-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2019-06-20 | — | — | US | disclosed |
| US-20180051034-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2018-02-22 | — | — | US | disclosed |
| EP-3268372-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2018-01-17 | — | — | EP | disclosed |
| EP-3268374-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2018-01-17 | — | — | EP | disclosed |
| CN-107548397-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107548396-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| US-20170369501-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATIONS | 4SC AG (DE) | 2017-12-28 | — | — | US | disclosed |
| WO-2016146575-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC DISCOVERY GMBH (DE) | 2016-09-22 | — | — | WO | disclosed |
| WO-2016146583-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC DISCOVERY GMBH (DE) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185483-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNA3, KCNN3, KCNK3 | CA12 4495/4885CA9 4240/4885TNF 3960/4885 |
| US-20180051034-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNN3, KCNN2, KCNA3 | CA12 3543/4885CA9 3456/4885TNF 4094/4885 |
| US-20170369501-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATIONS | KCNA3, KCNN3, KCNH3 | CA12 3899/4885CA9 2267/4885TNF 3517/4885 |
| US-20200339592-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNA3, KCNN3, KCNK3 | CA12 4495/4885CA9 4240/4885TNF 3960/4885 |
| US-10723743-B2 | Kv1.3 inhibitors and their medical application | KCNA3, KCNN3, KCNK3 | CA12 4495/4885CA9 4240/4885TNF 3960/4885 |
| US-10703735-B2 | 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer | POLRMT, COX4I1, UQCRC2 | CA12 4725/4885CA9 3901/4885TNF 4104/4885 |
| US-10822345-B2 | KV1.3 inhibitors and their medical application | KCNA3, KCNN3, KCNK3 | CA12 4495/4885CA9 4240/4885TNF 3960/4885 |
| US-10399991-B2 | Kv1.3 inhibitors and their medical applications | KCNA3, KCNN3, KCNH3 | CA12 3899/4885CA9 2267/4885TNF 3517/4885 |
| US-20200377514-A1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | KCNN3, KCNN2, KCNA3 | CA12 3543/4885CA9 3456/4885TNF 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.