Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665433 | 0.90 | C3AR1 (0.37) | EPHX2SMN1; SMN2CPB2 | |
| SCHEMBL27632265 | 0.81 | SMN1; SMN2 (0.45) | EPHX2SMN1; SMN2CPB2 | |
| SCHEMBL28786664 | 0.81 | CPB2 (0.46) | CPB2 | |
| SCHEMBL7628167 | 0.79 | EPHX2 (0.37) | EPHX2SMN1; SMN2CPB2ALB | |
| SCHEMBL32665488 | 0.79 | CPB2 (0.35) | CPB2 | |
| SCHEMBL1345737 | 0.79 | EPHX2 (0.37) | EPHX2SMN1; SMN2CPB2ALB | |
| SCHEMBL1343538 | 0.77 | USP2 (0.43) | SMN1; SMN2 | |
| SCHEMBL1343537 | 0.77 | USP2 (0.43) | SMN1; SMN2 | |
| SCHEMBL30861186 | 0.77 | CPB2 (0.44) | CPB2 | |
| SCHEMBL30058897 | 0.76 | FOLH1 (0.42) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180052161-A1 | BIOMARKERS FOR MALARIA DIAGNOSIS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2018-02-22 | — | — | US | disclosed |
| WO-2016149386-A1 | BIOMARKERS FOR MALARIA DIAGNOSIS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2016-09-22 | — | — | WO | disclosed |