SCHEMBL30058897

SCHEMBL30058897

O=C(O)CC[C@H](NC1CCCCO1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.42
▸ NAALAD2 Q9Y3Q0 3/20 0.42
▸ RIMKLA Q8IXN7 1/20 0.42
▸ EPHX2 P34913 1/20 0.40
▸ GGH Q92820 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665488 0.85 CPB2 (0.35) —
SCHEMBL31047745 0.84 KMT2A (0.36) FOLH1NAALAD2RIMKLAALDH1A1
SCHEMBL28786664 0.81 CPB2 (0.46) FOLH1
SCHEMBL32665433 0.78 C3AR1 (0.37) EPHX2
SCHEMBL18396446 0.77 LMNA (0.50) ALDH1A1
SCHEMBL30861186 0.77 CPB2 (0.44) FOLH1
SCHEMBL32665115 0.77 SMN1; SMN2 (0.33) —
SCHEMBL32665291 0.76 ITGB1 (0.31) —
SCHEMBL18075699 0.76 EPHX2 (0.35) EPHX2
SCHEMBL29501687 0.76 EPHX2 (0.53) FOLH1NAALAD2RIMKLAEPHX2GGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063554-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2024-05-24 — — CN disclosed
CN-118055773-A Lipopeptides inhibitors of interleukin-23 receptor 詹森生物科技公司 2024-05-17 — — CN disclosed
CN-118027153-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2024-05-14 — — CN disclosed
CN-118005736-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2024-05-10 — — CN disclosed
CN-118005737-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2024-05-10 — — CN disclosed
CN-116669710-A Compositions of peptide inhibitors of interleukin-23 receptor 詹森药业有限公司 2023-08-29 — — CN disclosed
CN-115298196-A Peptide inhibitors of the interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2022-11-04 — — CN disclosed
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