Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
| ▸ | CPN1 | P15169 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 3/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | OTC | P00480 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345737 | 1.00 | EPHX2 (0.37) | EPHX2SMN1; SMN2ALBC3AR1CPB2 | |
| SCHEMBL27632265 | 0.93 | SMN1; SMN2 (0.45) | EPHX2SMN1; SMN2CPB2 | |
| SCHEMBL29827128 | 0.82 | SMN1; SMN2 (0.42) | EPHX2SMN1; SMN2C3AR1CPB2MEN1 | |
| SCHEMBL30068909 | 0.80 | ALOX15 (0.39) | SMN1; SMN2C3AR1ALOX15ITGB3ITGA2B | |
| SCHEMBL29836396 | 0.80 | ALOX15 (0.39) | SMN1; SMN2C3AR1ALOX15ITGB3ITGA2B | |
| SCHEMBL466294 | 0.79 | C3AR1 (0.40) | EPHX2SMN1; SMN2C3AR1ALOX15ITGB3 | |
| SCHEMBL8164682 | 0.79 | C3AR1 (0.40) | EPHX2SMN1; SMN2C3AR1ALOX15ITGB3 | |
| SCHEMBL7196910 | 0.79 | GNPAT (0.46) | SMN1; SMN2C3AR1ALOX15ITGB3ITGA2B | |
| SCHEMBL408774 | 0.79 | GNPAT (0.46) | SMN1; SMN2C3AR1ALOX15ITGB3ITGA2B | |
| SCHEMBL12971304 | 0.79 | C3AR1 (0.43) | EPHX2SMN1; SMN2C3AR1ALOX15ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1660433-B | Combination of treating and/or preventing hemorrhoid | ZHENJUN WANG | 2011-09-07 | — | — | CN | claimed |
| CN-1660428-B | New application of synthase inhibitor of nitric in use for treating hemorrhoid | ZHENJUN WANG | 2011-09-07 | — | — | CN | claimed |
| CN-1234707-C | Anti-cancer chemicals of methotrexate derivatives and their uses in pharmaceutical science | CHINESE PHARMACEUTICAL UNIVERS (CN) | 2006-01-04 | — | — | CN | claimed |
| CN-1660433-A | Combination of treating and/or preventing hemorrhoid | WANG ZHENJUN (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-1660428-A | New application of synthase inhibitor of nitric in use for treating hemorrhoid | WANG ZHENJUN (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-1439641-A | Anti-cancer chemicals of methotrexate derivatives and their uses in pharmaceutical science | CHINESE PHARMACEUTICAL UNIV (CN) | 2003-09-03 | — | — | CN | claimed |
| US-20020081277-A1 | Methods and compositions for enhancing the immunostimulatory effect of interleukin-12 | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR, NIH | 2002-06-27 | — | — | US | claimed |
| US-6375944-B1 | Methods and compositions for enhancing the immunostimulatory effect of interleukin-12 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 2002-04-23 | — | — | US | claimed |
| CN-1660433-B | Combination of treating and/or preventing hemorrhoid | ZHENJUN WANG | 2011-09-07 | — | — | CN | disclosed |
| CN-1660428-B | New application of synthase inhibitor of nitric in use for treating hemorrhoid | ZHENJUN WANG | 2011-09-07 | — | — | CN | disclosed |
| CN-1234707-C | Anti-cancer chemicals of methotrexate derivatives and their uses in pharmaceutical science | CHINESE PHARMACEUTICAL UNIVERS (CN) | 2006-01-04 | — | — | CN | disclosed |
| CN-1660428-A | New application of synthase inhibitor of nitric in use for treating hemorrhoid | WANG ZHENJUN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1660433-A | Combination of treating and/or preventing hemorrhoid | WANG ZHENJUN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1439641-A | Anti-cancer chemicals of methotrexate derivatives and their uses in pharmaceutical science | CHINESE PHARMACEUTICAL UNIV (CN) | 2003-09-03 | — | — | CN | disclosed |
| US-20020081277-A1 | Methods and compositions for enhancing the immunostimulatory effect of interleukin-12 | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR, NIH | 2002-06-27 | — | — | US | disclosed |
| US-6375944-B1 | Methods and compositions for enhancing the immunostimulatory effect of interleukin-12 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 2002-04-23 | — | — | US | disclosed |