SCHEMBL32665488

SCHEMBL32665488

NCC[C@H](NC1CCCCO1)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 10/20 0.35
▸ LMNA P02545 1/20 0.31
▸ DPP7 Q9UHL4 2/20 0.31
▸ GABRR1 P24046 2/20 0.31
▸ ITGB1 P05556 1/20 0.31
▸ ITGA4 P13612 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28786664 0.90 CPB2 (0.46) CPB2
SCHEMBL30861186 0.85 CPB2 (0.44) CPB2
SCHEMBL30058897 0.85 FOLH1 (0.42) —
SCHEMBL32665433 0.81 C3AR1 (0.37) CPB2
SCHEMBL31047745 0.81 KMT2A (0.36) —
SCHEMBL18075699 0.79 EPHX2 (0.35) CPB2
SCHEMBL32665291 0.79 ITGB1 (0.31) ITGB1ITGA4
SCHEMBL18396446 0.77 LMNA (0.50) LMNA
SCHEMBL32665115 0.77 SMN1; SMN2 (0.33) LMNAITGB1ITGA4
SCHEMBL32665213 0.72 ITGB1 (0.32) ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 JANSSEN PHARMACEUTICA NV (BE) 2026-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 IL23R, IL17A, IL36G CPB2 1288/4885LMNA 1399/4885DPP7 201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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