Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 18/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 9/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 9/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593291 | 0.88 | KDM4E (0.66) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL14593292 | 0.79 | KDM4E (0.57) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17711245 | 0.77 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL16852472 | 0.77 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18077899 | 0.76 | MEN1 (0.42) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL19746100 | 0.75 | MEN1 (0.44) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL21028351 | 0.73 | KCNJ11 (0.54) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17298377 | 0.73 | KCNJ11 (0.50) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL3885735 | 0.72 | KDM4E (0.68) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL589730 | 0.72 | HPGD (0.67) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882710-B1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA | PHENEX PHARMACEUTICALS AG (DE) | 2016-09-07 | — | — | EP | disclosed |