Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 12/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934143 | 0.87 | CD38 (0.39) | CD38 | |
| SCHEMBL18073599 | 0.84 | EPHX2 (0.39) | CD38 | |
| SCHEMBL16666070 | 0.82 | JAK2 (0.39) | CD38ALDH1A1 | |
| SCHEMBL12018143 | 0.81 | EPHX2 (0.44) | CD38 | |
| SCHEMBL1425379 | 0.81 | CD38 (0.43) | CD38 | |
| SCHEMBL11878058 | 0.81 | CD38 (0.46) | CD38ALDH1A1 | |
| SCHEMBL10969412 | 0.79 | HTT (0.47) | CD38ALDH1A1 | |
| SCHEMBL2888808 | 0.77 | EPHX1 (0.39) | CD38 | |
| SCHEMBL23435085 | 0.75 | CD38 (0.52) | CD38NAMPT | |
| SCHEMBL24908113 | 0.74 | CD38 (0.43) | CD38ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RESEARCH, S.L. (ES) | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CYP4Z1, PNMT, HTR5A | CD38 869/4885NAMPT 1492/4885ALDH1A1 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.