Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808047 | 0.86 | L3MBTL1 (0.70) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL230453 | 0.82 | MAPT (0.65) | RAB9ANPC1MEN1ALDH1A1MAPT | |
| Bromide SCHEMBL5929889 | 0.80 | MAPT (0.63) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL28205325 | 0.79 | L3MBTL1 (0.59) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL94064 | 0.75 | — | — | |
| SCHEMBL3382178 | 0.74 | CYP1A2 (0.48) | L3MBTL1RAB9ANPC1MAPTCYP1A2 | |
| Bromide SCHEMBL1073577 | 0.73 | ALDH1A1 (0.51) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27578394 | 0.73 | ALDH1A1 (0.56) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 | |
| SCHEMBL6707340 | 0.73 | L3MBTL1 (0.51) | L3MBTL1RAB9ANPC1CYP1A2CYP2C19 | |
| SCHEMBL13151287 | 0.73 | CYP1A2 (0.48) | L3MBTL1RAB9ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051540-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2011-05-05 | — | — | WO | disclosed |