Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5929889 | 0.98 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL22887541 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1808115 | 0.82 | L3MBTL1 (0.54) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL12241845 | 0.81 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL28518579 | 0.81 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7105641 | 0.81 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7105645 | 0.81 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL220846 | 0.80 | RAB9A (0.97) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL12862528 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1368990 | 0.80 | ALDH1A1 (0.59) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777051-B | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-117777051-A | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-107228909-B | Method for measuring acotiamide hydrochloride raw material medicine and related substances in preparation thereof by using HPLC | 中美华世通生物医药科技(武汉)股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-109438437-B | Thiazole ring-containing anticancer compound | 深圳市第二人民医院 | 2020-07-17 | — | — | CN | claimed |
| CN-109438437-A | Anticancer compound of the one kind containing thiazole ring | 深圳市第二人民医院 | 2019-03-08 | — | — | CN | claimed |
| CN-108484443-A | A kind of cyanogen flutolanil compound and its preparation method and application with antibacterial activity | 华南农业大学 | 2018-09-04 | — | — | CN | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| CN-101193891-A | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA (JP) | 2008-06-04 | — | — | CN | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-4590666-A1 | THIAZOLE DERIVATIVES AS TAU AGGREGATION INHIBITORS | WisTa Laboratories Ltd. (SG) | 2025-07-30 | — | — | EP | disclosed |
| CN-119894874-A | Thiazole derivatives as TAU aggregation inhibitors | 维斯塔实验室有限公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-3885340-B1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORP (FI) | 2024-11-27 | — | — | EP | disclosed |
| CN-114630822-B | Biaryl dihydroorotate acid dehydrogenase inhibitors | 詹森生物科技公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-117777051-B | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2000058293-A2 | GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-05 | — | — | WO | disclosed |
| US-6121301-A | ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| CN-1261357-A | Process for preparing 2-hydroxybenzamide derivatives | ZERIA PHARM CO LTD (JP) | 2000-07-26 | — | — | CN | disclosed |
| EP-0994108-A1 | PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | MAPT 3579/4885ALDH1A1 1182/4885MEN1 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.