Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.59 |
| ▸ | FAP | Q12884 | 1/20 | 0.59 |
| ▸ | PEPD | P12955 | 4/20 | 0.49 |
| ▸ | XPNPEP1 | Q9NQW7 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15692884 | 0.88 | PEPD (0.49) | PREPFAPPEPDXPNPEP1POLB | |
| SCHEMBL17282584 | 0.86 | PREP (0.64) | PREPFAPPEPDDPP4DPP8 | |
| SCHEMBL11376449 | 0.85 | PREP (0.62) | PREPFAPPEPDACEREN | |
| SCHEMBL11376437 | 0.85 | PREP (0.62) | PREPFAPPEPDACEREN | |
| SCHEMBL15584468 | 0.84 | FKBP1A (0.48) | PREPFAPPEPDXPNPEP1POLB | |
| SCHEMBL23314580 | 0.84 | PREP (0.61) | PREPFAPPEPDDPP4DPP8 | |
| SCHEMBL11440574 | 0.84 | PREP (0.61) | PREPFAPPEPDDPP4DPP8 | |
| SCHEMBL7311829 | 0.83 | KLK5 (0.53) | PREPFAPPEPDXPNPEP1POLB | |
| SCHEMBL14235323 | 0.83 | KLK5 (0.53) | PREPFAPPEPDXPNPEP1POLB | |
| SCHEMBL17348390 | 0.83 | KLK5 (0.53) | PREPFAPPEPDXPNPEP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | DAO, DDC, HDGF | PREP 394/4885FAP 2167/4885PEPD 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.