Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13251158 | 0.84 | ACACA (0.51) | ACACAGPR84RAB9AABL1ABCB1 | |
| SCHEMBL13251116 | 0.84 | ACACA (0.51) | ACACAGPR84RAB9AADORA3NPC1 | |
| SCHEMBL13251026 | 0.84 | ACACA (0.51) | ACACAGPR84RAB9AABL1ABCB1 | |
| SCHEMBL13250997 | 0.84 | ACACA (0.51) | ACACAGPR84RAB9AADORA3NPC1 | |
| SCHEMBL12253350 | 0.83 | CYP11B2 (0.58) | ACACARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13408700 | 0.82 | ACACA (0.59) | ACACAGPR84RAB9ANPC1ABL1 | |
| SCHEMBL13251023 | 0.81 | ABL1 (0.52) | ACACARAB9ANPC1ABL1ABCB1 | |
| SCHEMBL28884088 | 0.81 | ACACA (0.46) | ACACAGPR84RAB9ANPC1MEN1 | |
| SCHEMBL28078075 | 0.80 | ALOX5 (0.43) | ACACAGPR84RAB9AADORA3NPC1 | |
| SCHEMBL27753123 | 0.80 | ADORA3 (0.43) | ACACAGPR84RAB9AADORA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109233813-A | A kind of near ultraviolet color organic electroluminescence device and preparation method thereof | 陕西师范大学 | 2019-01-18 | — | — | CN | claimed |
| US-11174211-B2 | Aryl compounds and polymers and methods of making and using the same | NEVADA RESEARCH & INNOVATION CORPORATION (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3271346-B1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | UNIV NEVADA RENO (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20210017110-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Board of Regents of the Nevada System Higher Education, on behalf of the University of Nevada, Reno (US) | 2021-01-21 | — | — | US | disclosed |
| US-20200331831-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) | 2020-10-22 | — | — | US | disclosed |
| US-10550056-B2 | Aryl compounds and polymers and methods of making and using the same | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2020-02-04 | — | — | US | disclosed |
| WO-2019173243-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2019-09-12 | — | — | WO | disclosed |
| CN-109233813-A | A kind of near ultraviolet color organic electroluminescence device and preparation method thereof | 陕西师范大学 | 2019-01-18 | — | — | CN | disclosed |
| WO-2016149633-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331831-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | AHR, TYR, PAH | ACACA 1570/4885GPR84 3999/4885RAB9A 2230/4885 |
| US-20210017110-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | AHR, PAH, ALKBH3 | ACACA 559/4885GPR84 3015/4885RAB9A 4743/4885 |
| US-11174211-B2 | Aryl compounds and polymers and methods of making and using the same | AHR, TYR, PAH | ACACA 1570/4885GPR84 3999/4885RAB9A 2230/4885 |
| US-10550056-B2 | Aryl compounds and polymers and methods of making and using the same | AHR, TYR, PAH | ACACA 1570/4885GPR84 3999/4885RAB9A 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.