Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306808 | 0.93 | CYP1A2 (0.47) | PRKCZNCOA1NCOA3APPMITF | |
| SCHEMBL18088198 | 0.81 | ADORA3 (0.44) | APPKDRALDH1A1HPGDHSD17B10 | |
| SCHEMBL10043606 | 0.80 | PRKCZ (0.55) | PRKCZNCOA1NCOA3APPMITF | |
| SCHEMBL16424628 | 0.79 | CYP3A4 (0.48) | PRKCZNCOA1NCOA3APPKIT | |
| SCHEMBL30516294 | 0.79 | CYP3A4 (0.48) | PRKCZNCOA1NCOA3APPKIT | |
| SCHEMBL28530131 | 0.79 | CYP1A2 (0.44) | PRKCZNCOA1NCOA3APPKIT | |
| SCHEMBL28406194 | 0.77 | PRKCZ (0.51) | PRKCZNCOA1NCOA3APPMITF | |
| SCHEMBL30034553 | 0.77 | ALDH1A1 (0.44) | PRKCZNCOA1NCOA3APPKIT | |
| SCHEMBL9561191 | 0.77 | ALDH1A1 (0.44) | PRKCZNCOA1NCOA3APPKIT | |
| SCHEMBL23332525 | 0.77 | GPR84 (0.48) | ALDH1A1HPGDHSD17B10CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271346-B1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | UNIV NEVADA RENO (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2019173243-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2016149633-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2016-09-22 | — | — | WO | disclosed |