SCHEMBL1808946

SCHEMBL1808946

O=S(=O)(O)c1ccc(O)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
NSD2 O96028 1/20 0.45
MMP14 P50281 1/20 0.45
CASP6 P55212 1/20 0.45
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
TTR P02766 2/20 0.43
POLB P06746 1/20 0.42
ESR1 P03372 6/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
ESR2 Q92731 4/20 0.39
PTGS1 P23219 1/20 0.39
EGFR P00533 1/20 0.39
PDK2 Q15119 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28047309 0.98 HSD17B10 (0.48) HSD17B10NSD2MMP14CASP6LMNA
SCHEMBL69469 0.84 HSD17B10 (0.52) HSD17B10TTRPOLBESR1CA12
SCHEMBL15880399 0.83 TRPV4 (0.53) HSD17B10HPGDTTRPOLBESR1
SCHEMBL10422867 0.83 HSD17B10 (0.50) HSD17B10NSD2MMP14CASP6LMNA
SCHEMBL1657155 0.81 HSD17B10 (0.48) HSD17B10TTRPOLBESR1CA12
Hydrochloric Acid SCHEMBL28299767 0.81 POLB (0.49) HSD17B10NSD2MMP14CASP6LMNA
SCHEMBL1805100 0.81 CA1 (0.50) HSD17B10LMNAPOLBESR1CA12
SCHEMBL1729184 0.80 HSD11B1 (0.45) HSD17B10LMNAHPGDTSHR
SCHEMBL30678861 0.80 HSD11B1 (0.45) HSD17B10LMNAHPGDTSHR
SCHEMBL5664509 0.79 LMNA (0.53) HSD17B10NSD2MMP14CASP6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333474-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2023-10-19 US disclosed
CN-116744978-A anti-HER 2 immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2023-09-12 CN disclosed
CN-105027005-B Composition for forming resist underlayer film containing aryl sulfonate having hydroxyl group 日产化学工业株式会社 2020-02-07 CN disclosed
CN-108976103-A A kind of green synthesis method of 2,5- chlorophenesic acid 山东理工大学 2018-12-11 CN disclosed
CN-108463728-A Isobaric and ectopic mass marker 电泳有限公司 2018-08-28 CN disclosed
US-9395628-B2 Resist underlayer film-forming composition containing aryl sulfonate salt having hydroxyl group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-07-19 US disclosed
US-20150378260-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING ARYL SULFONATE SALT HAVING HYDROXYL GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-31 US disclosed
CN-104447219-A Method for synthesizing dicamba key intermediate 2,5-dichlorophenol UNIV HANGZHOU NORMAL 2015-03-25 CN disclosed
CN-103534233-A Heterobifunctional esters for use in labeling target molecules LIFE TECHNOLOGIES CORP 2014-01-22 CN disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 HSD17B10 2848/4885NSD2 1137/4885MMP14 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.