Sugi Predict

Sugi Predict / Compounds / SCHEMBL18090465

SCHEMBL18090465

SCHEMBL18090465

c1ccc2cc(N(c3cc(-c4ccc5c(c4)sc4ccccc45)cc(N(c4ccc5ccccc5c4)c4ccc5c(c4)sc4ccccc45)c3)c3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GPR3 P46089 1/20 0.37
▸ ESR1 P03372 1/20 0.31
▸ ESR2 Q92731 1/20 0.31
▸ ALOX5 P09917 1/20 0.30
▸ LIMK1 P53667 1/20 0.30
▸ PMM2 O15305 1/20 0.30
▸ MPI P34949 1/20 0.30
▸ PHOSPHO1 Q8TCT1 1/20 0.30
▸ S1PR4 O95977 1/20 0.30
▸ S1PR5 Q9H228 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18090658 0.92 ALDH1A1 (0.33) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL27273510 0.91 ALDH1A1 (0.41) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL18090414 0.90 ALDH1A1 (0.37) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL20109520 0.90 LIMK1 (0.33) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL25534480 0.90 ALDH1A1 (0.39) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL17806966 0.90 GPR3 (0.37) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL27274333 0.90 ALDH1A1 (0.39) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL25535334 0.90 ALDH1A1 (0.39) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL24471753 0.89 ALDH1A1 (0.41) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL17806958 0.88 ALDH1A1 (0.38) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392359-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-08-27 — — US disclosed
US-20180072695-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-15 — — US disclosed
US-20180072695-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-15 — — US disclosed
WO-2016148425-A2 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC APPARATUS FOR SAME 덕산네오룩스 주식회사 2016-09-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072695-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 ALDH1A1 493/4885HPGD 3454/4885MAPT 2943/4885
US-10392359-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 ALDH1A1 493/4885HPGD 3454/4885MAPT 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.