Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18090578 | 0.88 | CASR (0.50) | ALDH1A1KMT2ALMNAKDM4ETSHR | |
| SCHEMBL17888987 | 0.77 | KMT2A (0.44) | ALDH1A1KMT2AHPGDLMNAKDM4E | |
| SCHEMBL28092846 | 0.75 | MEN1 (0.58) | ALDH1A1KMT2AHPGDKDM4EMMP3 | |
| SCHEMBL16691260 | 0.74 | GAA (0.54) | ALDH1A1KMT2ATSHRGAASMN1; SMN2 | |
| SCHEMBL27249544 | 0.72 | LMNA (0.47) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL16691268 | 0.70 | TRPM8 (0.45) | ALDH1A1KMT2AMMP3GAABMP1 | |
| SCHEMBL2376923 | 0.70 | SIGMAR1 (0.76) | ALDH1A1KMT2ALMNATSHRMMP3 | |
| SCHEMBL3829272 | 0.69 | CYP2C9 (0.50) | KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL29336734 | 0.69 | CYP2D6 (0.48) | ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL12015839 | 0.68 | PKM (0.43) | ALDH1A1KMT2AKDM4EMMP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9440954-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-13 | — | — | US | disclosed |
| US-9440954-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-13 | — | — | US | disclosed |
| CN-104334542-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2015-02-04 | — | — | CN | disclosed |