Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765600 | 0.87 | ALDH1A1 (0.38) | ACHEALDH1A1CYP3A4TUBB1MAPT | |
| SCHEMBL30735735 | 0.83 | ALDH1A1 (0.38) | ACHEALDH1A1CYP3A4TUBB1MAPT | |
| SCHEMBL21949630 | 0.77 | MAPT (0.43) | ALDH1A1CYP3A4TUBB1MAPTNPSR1 | |
| SCHEMBL3596792 | 0.77 | POLB (0.42) | ACHEALDH1A1CYP3A4TUBB1MAPT | |
| SCHEMBL20149289 | 0.77 | MAPT (0.39) | ALDH1A1CYP3A4TUBB1MAPTNPSR1 | |
| SCHEMBL524923 | 0.74 | MAPT (0.40) | ACHEALDH1A1CYP3A4TUBB1MAPT | |
| SCHEMBL27185258 | 0.74 | MAPT (0.55) | ACHEALDH1A1CYP3A4MAPTNPSR1 | |
| SCHEMBL16059989 | 0.74 | ALDH1A1 (0.44) | ACHEALDH1A1CYP3A4MAPTNPSR1 | |
| SCHEMBL25162229 | 0.73 | ALDH1A1 (0.36) | ALDH1A1CYP3A4MAPTPOLBTSHR | |
| SCHEMBL9846429 | 0.73 | ALDH1A1 (0.45) | ACHEALDH1A1CYP3A4MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257641-A1 | NOVEL ALKYLENE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257641-A1 | NOVEL ALKYLENE DERIVATIVES | ACSS2, ACACB, ADCY2 | ACHE 793/4885ALDH1A1 288/4885CYP3A4 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.