Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853943 | 0.87 | MAPT (0.44) | RBP4SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL4855770 | 0.87 | KMT2A (0.48) | HTR1AADRA1BSMN1; SMN2GAALMNA | |
| SCHEMBL4857745 | 0.85 | AKR1C3 (0.56) | TSHRALDH1A1 | |
| SCHEMBL4251027 | 0.85 | GPR119 (0.46) | SMN1; SMN2GAALMNAMEN1KMT2A | |
| SCHEMBL27671019 | 0.84 | RBP4 (0.44) | RBP4GAALMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4855946 | 0.81 | HTR1A (0.43) | HTR1AADRA1BGAALMNAMEN1 | |
| SCHEMBL18092205 | 0.80 | TSHR (0.50) | HTR1AADRA1BRBP4SMN1; SMN2MEN1 | |
| SCHEMBL4857386 | 0.80 | HTR1A (0.49) | HTR1ALMNATSHRMAPT | |
| Hydrochloric Acid SCHEMBL4859541 | 0.79 | HTR1A (0.50) | HTR1AADRA1BLMNA | |
| SCHEMBL27752291 | 0.79 | HTR1A (0.45) | HTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100526301-C | 1, 2-di (cyclic) substituted benzene compounds | EISAI R&D MAN CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
| CN-1902170-A | 1, 2-di (cyclic) substituted benzene compounds | EISAI R&D MAN CO LTD (JP) | 2007-01-24 | — | — | CN | disclosed |