Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4858136 | 1.00 | LGMN (0.37) | LGMNALDH1A1IDH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4857455 | 0.89 | ALDH1A1 (0.40) | LGMNALDH1A1KMT2AMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4848631 | 0.87 | DRD2 (0.37) | LGMNALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4255006 | 0.85 | KDM4E (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL4858120 | 0.85 | KDM4E (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL4856031 | 0.85 | OPRD1 (0.36) | LGMNPRKDC | |
| Hydrochloric Acid SCHEMBL4857827 | 0.84 | KDM4E (0.40) | LMNA | |
| Hydrochloric Acid SCHEMBL4853839 | 0.84 | MAPT (0.36) | LGMNALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4854981 | 0.84 | EBP (0.35) | LMNAHPGDSMN1; SMN2PRKDC | |
| Hydrochloric Acid SCHEMBL4852039 | 0.83 | PRKDC (0.37) | LGMNALDH1A1L3MBTL1HPGDPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |