Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729744 | 1.00 | HDAC4 (0.51) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL198138 | 0.94 | HDAC4 (0.56) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL17973756 | 0.88 | HDAC4 (0.43) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL9656296 | 0.85 | PTGS2 (0.48) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL8419562 | 0.85 | CYP17A1 (0.50) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL16629816 | 0.83 | HDAC4 (0.47) | HDAC4HDAC2HDAC8TAAR1ALDH1A1 | |
| SCHEMBL1006801 | 0.83 | HDAC4 (0.62) | HDAC4HDAC2HDAC8TAAR1LMNA | |
| SCHEMBL6248963 | 0.82 | TAAR1 (0.67) | RXRARXRBRXRGCTSLCTSS | |
| SCHEMBL17973741 | 0.81 | HDAC4 (0.43) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL17973754 | 0.81 | HDAC4 (0.43) | HDAC4HDAC2HDAC8RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063154-B1 | CROSS-COUPLING OF UNACTIVATED SECONDARY BORONIC ACIDS | UNIV ILLINOIS (US) | 2023-08-30 | — | — | EP | disclosed |
| US-10072028-B2 | Cross-coupling of unactivated secondary boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-09-11 | — | — | US | disclosed |
| US-20160280721-A1 | CROSS-COUPLING OF UNACTIVATED SECONDARY BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280721-A1 | CROSS-COUPLING OF UNACTIVATED SECONDARY BORONIC ACIDS | BOLA2; BOLA2B, BLVRB, CD79B | HDAC4 4110/4885HDAC2 3208/4885HDAC8 3868/4885 |
| US-10072028-B2 | Cross-coupling of unactivated secondary boronic acids | BOLA2; BOLA2B, BLVRB, CD79B | HDAC4 4110/4885HDAC2 3208/4885HDAC8 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.