Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198138 | 0.87 | HDAC4 (0.56) | PTGS2HDAC4HDAC2HDAC8RXRA | |
| SCHEMBL25909341 | 0.86 | RXRA (0.56) | PTGS2HDAC4HDAC2HDAC8RXRA | |
| SCHEMBL18092986 | 0.85 | HDAC4 (0.51) | PTGS2HDAC4HDAC2HDAC8RXRA | |
| SCHEMBL8729744 | 0.85 | HDAC4 (0.51) | PTGS2HDAC4HDAC2HDAC8RXRA | |
| SCHEMBL17809807 | 0.83 | PTPN5 (0.51) | PTGS2RXRARXRBRXRGBCL2 | |
| SCHEMBL19027079 | 0.81 | TSHR (0.47) | PTGS2UCHL1ALDH1A1USP2GAA | |
| SCHEMBL24015316 | 0.80 | HDAC4 (0.53) | PTGS2HDAC4HDAC2HDAC8BCL2 | |
| SCHEMBL8419562 | 0.79 | CYP17A1 (0.50) | HDAC4HDAC2HDAC8RXRARXRB | |
| SCHEMBL11326904 | 0.79 | BCL2 (0.53) | PTGS2BCL2EDNRBEDNRA | |
| SCHEMBL17973756 | 0.79 | HDAC4 (0.43) | PTGS2HDAC4HDAC2HDAC8RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475926-A2 | Oxidation of dialkyl polyaromatics to dicarboxypolyaromatics | MONSANTO COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |