SCHEMBL1808182

SCHEMBL1808182

O=C(Oc1ccccc1)Oc1ccc2ccccc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.65
MAPT P10636 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
MEN1 O00255 2/20 0.65
PTPN7 P35236 1/20 0.55
ALDH1A1 P00352 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HSD17B10 Q99714 1/20 0.53
FABP7 O15540 1/20 0.51
FABP3 P05413 1/20 0.51
PPARG P37231 4/20 0.50
NCOA2 Q15596 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
MMP1 P03956 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MMP12 P39900 1/20 0.49
BCHE P06276 1/20 0.47
FAAH O00519 1/20 0.47
EPHX1 P07099 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1809377 0.94 KMT2A (0.66) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL17641642 0.87 KMT2A (0.54) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL361288 0.87 ESR1 (0.53) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL11444479 0.86 KMT2A (0.61) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL1624304 0.85 KMT2A (0.52) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL29937281 0.83 KMT2A (0.69) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL1563903 0.83 KMT2A (0.69) KMT2AMAPTTDP1MEN1PTPN7
Naphthalene SCHEMBL1131780 0.83 KMT2A (0.69) KMT2AMAPTTDP1MEN1PTPN7
Bicarbonate SCHEMBL28016108 0.83 ESR1 (0.53) KMT2AMAPTTDP1MEN1PTPN7
SCHEMBL10596262 0.83 KMT2A (0.58) KMT2AMAPTTDP1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
CN-108290820-B Method for recovering aromatic alcohol from melt polymerization and system for recovering same 沙特基础工业全球技术有限公司 2021-10-01 CN disclosed
CN-104837804-B The method for manufacturing diaryl carbonate 科思创德国股份有限公司 2017-12-22 CN disclosed
US-9765012-B2 Method for producing diaryl carbonate COVESTRO DEUTSCHLAND AG (DE) 2017-09-19 US disclosed
EP-2935197-B1 METHOD FOR MANUFACTURING DIARYL CARBONATE COVESTRO DEUTSCHLAND AG (DE) 2017-07-12 EP disclosed
EP-2239249-B1 Method for producing diarylcarbonates or arylalkylcarbonates from dialkylcarbonates COVESTRO DEUTSCHLAND AG (DE) 2017-05-10 EP disclosed
EP-2322261-B1 Method for cleaning dialkyl carbonates COVESTRO DEUTSCHLAND AG (DE) 2016-12-21 EP disclosed
EP-2062868-B1 Process for purifying diaryl carbonates COVESTRO DEUTSCHLAND AG (DE) 2016-02-24 EP disclosed
US-20160002143-A1 METHOD FOR PRODUCING DIARYL CARBONATE BAYER MATERIALSCIENCE AG (DE) 2016-01-07 US disclosed
US-20100261928-A1 PROCESS FOR PREPARING DIARYL CARBONATES OR ALKYL ARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2010-10-14 US disclosed
EP-2239249-A1 Method for producing diarylcarbonates or arylalkylcarbonates from dialkylcarbonates Bayer MaterialScience AG (DE) 2010-10-13 EP disclosed
US-20100010252-A1 PROCESS FOR PREPARING DIARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2010-01-14 US disclosed
EP-2135857-A2 Method for manufacturing diaryl carbonates from dialkyl carbonates Bayer Material Science AG (DE) 2009-12-23 EP disclosed
US-20090137832-A1 PROCESSES FOR PURIFYING DIARYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
EP-2062868-A2 Process for purifying diaryl carbonates Bayer MaterialScience AG (DE) 2009-05-27 EP disclosed
EP-2036880-A2 Method for producing diarylcarbonates or arylalkylcarbonates from dialkylcarbonates Bayer MaterialScience AG (DE) 2009-03-18 EP disclosed
EP-1995233-A2 Method for producing diarylcarbonates or arylalkylcarbonates from dialkylcarbonates Bayer MaterialScience AG (DE) 2008-11-26 EP disclosed
EP-0287121-B1 HEAT AND LIGHT-SENSITIVE RECORDING MATERIAL AND RECORDING METHOD JUJO PAPER CO., LTD. (JP) 1993-08-04 EP disclosed
EP-0287121-A2 Heat and light-sensitive recording material and recording method JUJO PAPER CO., LTD. (JP) 1988-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002143-A1 METHOD FOR PRODUCING DIARYL CARBONATE PGLS, ALPG, DPAGT1 KMT2A 1635/4885MAPT 4363/4885TDP1 3824/4885
US-20090137832-A1 PROCESSES FOR PURIFYING DIARYL CARBONATES DHCR7, HSD11B1, AGL KMT2A 598/4885MAPT 4164/4885TDP1 1809/4885
US-20100261928-A1 PROCESS FOR PREPARING DIARYL CARBONATES OR ALKYL ARYL CARBONATES FROM DIALKYL CARBONATES HDHD5, AHR, AGL KMT2A 751/4885MAPT 4584/4885TDP1 3806/4885
US-20100010252-A1 PROCESS FOR PREPARING DIARYL CARBONATES FROM DIALKYL CARBONATES ADH1C, TET2, AKR1C4 KMT2A 1147/4885MAPT 4612/4885TDP1 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.