Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751456 | 0.82 | SOS1 (0.45) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL30498167 | 0.82 | SOS1 (0.45) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL1228180 | 0.82 | HSD17B10 (0.47) | NOTUMSLC6A3ABL1SOS1PDK2 | |
| SCHEMBL20076067 | 0.81 | NOTUM (0.42) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL1516592 | 0.81 | GAA (0.44) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL21198962 | 0.81 | NOTUM (0.42) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL29570702 | 0.81 | NOTUM (0.42) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL16088526 | 0.81 | CA12 (0.44) | NOTUMSLC6A3ABL1PDK2NR4A2 | |
| SCHEMBL23526170 | 0.79 | SOS1 (0.54) | NOTUMSLC6A3SOS1PDK2NR4A2 | |
| SCHEMBL22492252 | 0.79 | SOS1 (0.43) | NOTUMSLC6A3ABL1SOS1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836732-B2 | Compounds for combating arthropods | BAYER ANIMAL HEALTH GMBH (DE) | 2020-11-17 | — | — | US | disclosed |
| US-10150737-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-12-11 | — | — | US | disclosed |
| US-9758485-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-12 | — | — | US | disclosed |
| WO-2016174052-A1 | ANTIPARASITIC COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2016-11-03 | — | — | WO | disclosed |
| US-20160297765-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160280668-A1 | NOVEL COMPOUNDS FOR COMBATING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-09-29 | — | — | US | disclosed |
| US-20160278379-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836732-B2 | Compounds for combating arthropods | PRDX4, SERPINB6, GSTA1 | NOTUM 2064/4885SLC6A3 3248/4885ABL1 2785/4885 |
| US-20160278379-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | CYP4X1, CYP4B1, SERPINB6 | NOTUM 1558/4885SLC6A3 4216/4885ABL1 3006/4885 |
| US-10150737-B2 | Compounds for controlling arthropods | SERPINB6, CYP4X1, C1S | NOTUM 1907/4885SLC6A3 3886/4885ABL1 2355/4885 |
| US-20160280668-A1 | NOVEL COMPOUNDS FOR COMBATING ARTHROPODS | PRDX4, CYP4X1, PRDX1 | NOTUM 1936/4885SLC6A3 3949/4885ABL1 3117/4885 |
| US-20160297765-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | CYP4X1, CYP4B1, SERPINB6 | NOTUM 1558/4885SLC6A3 4216/4885ABL1 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.