Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18094465 | 0.88 | MPL (0.49) | MPLMAPTADORA3RXFP1LMNA | |
| SCHEMBL16718882 | 0.87 | MPL (0.51) | MPLMAPTADORA3TP53 | |
| SCHEMBL18094557 | 0.86 | MAPT (0.53) | MPLMAPTADORA3RXFP1LMNA | |
| SCHEMBL18094550 | 0.86 | ADORA3 (0.44) | MAPTADORA3RXFP1TRPV1 | |
| SCHEMBL18094497 | 0.85 | LSS (0.46) | MPLMAPTADORA3RXFP1LMNA | |
| SCHEMBL18094535 | 0.83 | MAPT (0.44) | MPLMAPTADORA3RXFP1LMNA | |
| SCHEMBL18094573 | 0.83 | ADORA3 (0.53) | MAPTADORA3TP53 | |
| SCHEMBL18094473 | 0.83 | KDM4E (0.45) | MPLMAPTADORA3RXFP1LMNA | |
| SCHEMBL18094467 | 0.82 | BRAF (0.47) | MPLMAPT | |
| SCHEMBL18094532 | 0.82 | TRPV1 (0.45) | MPLMAPTADORA3RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202849-A1 | ANTIPARASITIC COMPOUNDS | AVISTA PHARMA SOLUTIONS, INC. | 2017-07-20 | — | — | US | claimed |
| US-9643963-B2 | Antiparasitic compounds | AVISTA PHARMA SOLUTIONS, INC. (US) | 2017-05-09 | — | — | US | claimed |
| US-20160280700-A1 | ANTIPARASITIC COMPOUNDS | SNAPDRAGON CHEMISTRY, INC. | 2016-09-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280700-A1 | ANTIPARASITIC COMPOUNDS | TPP2, TPP1, SERPINB1 | MPL 598/4885MAPT 2921/4885ADORA3 648/4885 |
| US-20170202849-A1 | ANTIPARASITIC COMPOUNDS | TPP2, TPP1, SERPINB1 | MPL 598/4885MAPT 2921/4885ADORA3 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.