SCHEMBL1809562

SCHEMBL1809562

O=C(S)Cc1nnc(S)s1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.39
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2809863 0.86 F2 (0.45) F2HTTHSD17B10SMN1; SMN2NPC1
SCHEMBL10403239 0.83 F2 (0.39) F2HTTHSD17B10SMN1; SMN2NPC1
SCHEMBL10769562 0.81 F2 (0.62) F2HTTHSD17B10SMN1; SMN2NPC1
SCHEMBL11590351 0.79 TSHR (0.33)
SCHEMBL10404084 0.76 F2 (0.39) F2HTTHSD17B10SMN1; SMN2NPC1
SCHEMBL9800507 0.76 HSD17B10 (0.64) F2HTTHSD17B10SMN1; SMN2NPC1
SCHEMBL4444193 0.74 ALDH1A1 (0.40)
SCHEMBL11453155 0.74 SMN1; SMN2 (0.57) HTTHSD17B10SMN1; SMN2RAB9A
SCHEMBL8770491 0.72
SCHEMBL5655863 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117399635-A Gold nanoparticle and preparation method and application thereof 中国科学院遗传与发育生物学研究所 2024-01-16 CN claimed
JP-52079081-A None JP disclosed
EP-1801108-B9 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2013-11-20 EP disclosed
EP-1801108-B1 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2012-11-14 EP disclosed
US-20110210007-A1 ZINCATE ZINC PLATING BATH YUKEN INDUSTRY CO., LTD. (JP) 2011-09-01 US disclosed
EP-2357268-A1 ZINCATE ZINC PLATING BATH Yuken Industry Co., Ltd. (JP) 2011-08-17 EP disclosed
US-7935700-B2 Morpholine compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-05-03 US disclosed
US-20070265257-A1 Morpholine Compound MITSUBISHI PHARMA CORPORATION (JP) 2007-11-15 US disclosed
EP-1801108-A1 MORPHOLINE COMPOUND Mitsubishi Pharma Corporation (JP) 2007-06-27 EP disclosed
US-4656262-A 7-methoxy cephalosporin derivative YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-04-07 US disclosed
US-4242449-A 7-Methoxy cephalosporins and process of producing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
US-4165429-A 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1979-08-21 US disclosed
US-4068074-A BACTERICIDES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1978-01-10 US disclosed
JP-S5279081-A PREPARATION OF NOVEL 7-METHOXYCEPHALOSPORINS YAMANOUCHI PHARMACEUT CO LTD 1977-07-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265257-A1 Morpholine Compound CCR3, CCR1, CCR4 F2 3002/4885HTT 2964/4885HSD17B10 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.