Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL28386839 | 1.00 | THRB (0.65) | THRBCA5ACA5BALDH1A1LMNA | |
| Nitric Acid SCHEMBL961471 | 1.00 | THRB (0.65) | THRBCA5ACA5BALDH1A1LMNA | |
| Nitric Acid SCHEMBL11782416 | 0.84 | THRB (0.44) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL711997 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL8430202 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL7035160 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL124052 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL2220986 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL854170 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA | |
| Glycerin SCHEMBL28512738 | 0.84 | LMNA (0.56) | THRBCA5ACA5BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618819-B2 | Para-aminobenzoic acid sensitized terbium doped LaF3 nanoparticles for detection of explosive nitro compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-04-14 | — | — | US | claimed |
| US-20170225963-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-10 | — | — | US | claimed |
| EP-3194936-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | Council of Scientific and Industrial Research (IN) | 2017-07-26 | — | — | EP | claimed |
| WO-2016020939-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-02-11 | — | — | WO | claimed |
| JP-2001517697-A | — | — | 2001-10-09 | — | — | JP | claimed |
| EP-1019038-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME | RHODES, John (GB) | 2000-07-19 | — | — | EP | claimed |
| WO-1999016436-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME | RHODES JOHN (GB) | 1999-04-08 | — | — | WO | claimed |
| CN-114085128-B | Method for separating and purifying 1,2,4-butanetriol based on difunctional ionic liquid | 中国科学院过程工程研究所 | 2024-02-20 | — | — | CN | disclosed |
| CN-114085128-A | Method for separating and purifying 1,2,4-butanetriol based on bifunctional ionic liquid | 雅邦绿色过程与新材料研究院南京有限公司 | 2022-02-25 | — | — | CN | disclosed |
| US-10618819-B2 | Para-aminobenzoic acid sensitized terbium doped LaF3 nanoparticles for detection of explosive nitro compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-04-14 | — | — | US | disclosed |
| US-20170225963-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-10 | — | — | US | disclosed |
| EP-3194936-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | Council of Scientific and Industrial Research (IN) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016020939-A1 | PARA-AMINOBENZOIC ACID SENSITIZED TERBIUM DOPED LAF3 NANOPARTICLES FOR DETECTION OF EXPLOSIVE NITRO COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-02-11 | — | — | WO | disclosed |
| EP-1019038-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME | RHODES, John (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999016436-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME | RHODES JOHN (GB) | 1999-04-08 | — | — | WO | disclosed |
| US-5504117-A | Pharmacologic preparation for the treatment of anal disorders | NEPTUNE PHARMACEUTICAL CORPORATION (US) | 1996-04-02 | — | — | US | disclosed |