SCHEMBL18096367

SCHEMBL18096367

C=CCN(CC=C)c1c(C)cc(C)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 7/20 0.47
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
GAA P10253 1/20 0.32
C5AR1 P21730 1/20 0.32
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
HTR1D P28221 1/20 0.31
HTR1B P28222 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR1E P28566 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR7 P34969 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129148 0.83 CYP3A4 (0.38) CRHR1KMT2AADRA1AOPRK1HTR2B
SCHEMBL11376288 0.78 CRHR1 (0.33) CRHR1
SCHEMBL15324519 0.77 CRHR1 (0.41) CRHR1C5AR1HTR1AADRA2ADRD2
SCHEMBL21611342 0.77 CRHR1 (0.41) CRHR1KMT2ASMN1; SMN2C5AR1HTR1D
SCHEMBL14328255 0.77 ESR1 (0.37) CRHR1KMT2ASMN1; SMN2GAASLC6A4
SCHEMBL1688846 0.75 CRHR1 (0.40) CRHR1KMT2ASMN1; SMN2C5AR1HTR1A
SCHEMBL8103789 0.73 CRHR1 (0.37) CRHR1KMT2ASMN1; SMN2GAALMNA
SCHEMBL11473651 0.73 CRHR1 (0.37) CRHR1KMT2ASMN1; SMN2GAALMNA
SCHEMBL10981799 0.72 CRHR1 (0.36) CRHR1SMN1; SMN2GAALMNA
SCHEMBL8043350 0.71 CRHR1 (0.33) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174757-A1 Linear Low Density Polyethylene for Film Applications EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-06-08 US disclosed
EP-3452520-B1 TETRAHYDRO-AS-INDACENYL CATALYST COMPOSITION, CATALYST SYSTEM, AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-05-18 EP disclosed
US-20220048016-A1 Supported Catalyst Systems and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-02-17 US disclosed
US-10954328-B2 Polymerization processes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-03-23 US disclosed
US-10822434-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-11-03 US disclosed
US-20200332031-A1 METALLOCENES WITH TWO -SI-SI- BRIDGES EXXONMOBIL CHEMICAL PATENTS INC. 2020-10-22 US disclosed
EP-3022235-B1 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-04-08 EP disclosed
US-20190275506-A1 Catalyst Systems Comprising Activator, Polymerization Processes Using Same, and Products Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2019-09-12 US disclosed
WO-2019173131-A1 CATALYST SYSTEMS COMPRISING ACTIVATOR, POLYMERIZATION PROCESSES USING SAME, AND PRODUCTS MADE THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-12 WO disclosed
US-20190248929-A1 Benzindenyl Catalyst Systems and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2019-08-15 US disclosed
US-20190144579-A1 Polymerization Processes EXXONMOBIL CHEMICAL PATENTS INC. 2019-05-16 US disclosed
US-20190119413-A1 Catalyst Systems and Polymerization Processes for Using the Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-25 US disclosed
WO-2018182860-A1 SOLUTION PROCESS TO MAKE ETHYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-10-04 WO disclosed
WO-2018067289-A1 STERICALLY HINDERED METALLOCENES, SYNTHESIS AND USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-04-12 WO disclosed
WO-2018048533-A1 GROUP 3 METAL CATALYST SYSTEM AND PROCESS TO PRODUCE ETHYLENE POLYMERS THEREWITH EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-03-15 WO disclosed
WO-2018022238-A1 CATALYST COMPOSITIONS AND USE THEREOF EXXONMOBILE CHEMICAL PATENTS INC. (US) 2018-02-01 WO disclosed
EP-3274378-A1 GROUP 6 TRANSITION METAL CATALYST COMPOUND AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2018-01-31 EP disclosed
US-20170320976-A1 TETRAHYDRO-AS-INDACENYL CATALYST COMPOSITION, CATALYST SYSTEM, AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2017-11-09 US disclosed
WO-2016153574-A1 GROUP 6 TRANSITION METAL CATALYST COMPOUND AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-29 WO disclosed
US-9079911-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2015-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320976-A1 TETRAHYDRO-AS-INDACENYL CATALYST COMPOSITION, CATALYST SYSTEM, AND PROCESSES FOR USE THEREOF MLX, TXN, TSNAX CRHR1 4766/4885KMT2A 1268/4885SMN1; SMN2 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.