Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18096367 | 0.71 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL11129148 | 0.68 | CYP3A4 (0.38) | CRHR1CYP3A4 | |
| SCHEMBL6580919 | 0.67 | S100B (0.62) | CRHR1CYP3A4TSHR | |
| SCHEMBL11376288 | 0.64 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL1050286 | 0.64 | USP2 (0.33) | TSHR | |
| SCHEMBL9153229 | 0.63 | S100B (0.72) | CRHR1CYP3A4TSHRMAPK1 | |
| SCHEMBL14328255 | 0.63 | ESR1 (0.37) | CRHR1CYP3A4TSHRMAPK1 | |
| SCHEMBL11045130 | 0.63 | CYP3A4 (0.39) | CYP3A4TSHR | |
| SCHEMBL2120713 | 0.63 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1 | |
| SCHEMBL476444 | 0.63 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| US-5874426-A | USEFUL IN THE TREATMENT OF STROKE, CEREBRAL ISCHEMIA, OR CEREBRAL INFARCTION RESULTING FROM THROMBOEMBOLIC OR HEMORRHAGIC STROKE, CEREBRAL VASOSPASMS, HYPOGLYCEMIA, CARDIAC ARREST, STATUS EPILEPTICUS, ANOXIA, SEIZURE DISORDER | WARNER-LAMBERT COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1996040651-A1 | ALKYL AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |