Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466415 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9945928 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL18100115 | 0.78 | TGM2 (0.58) | LMNA | |
| SCHEMBL2735680 | 0.77 | HSD17B10 (0.65) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2384797 | 0.77 | ALDH1A1 (0.65) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL11866935 | 0.77 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL26386086 | 0.77 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13391043 | 0.77 | HSD17B10 (0.67) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2474191 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL25144828 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280827-A1 | POLYMERS, HYDROGELS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280827-A1 | POLYMERS, HYDROGELS, AND USES THEREOF | BOLA2; BOLA2B, PARG, BRAP | SMN1; SMN2 3359/4885LMNA 780/4885ALDH1A1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.