SCHEMBL1810087

SCHEMBL1810087

C=C(C)C1CC=C(C(=O)OC)CC1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.69
LMNA P02545 2/20 0.69
TRPA1 O75762 1/20 0.51
TRPV1 Q8NER1 1/20 0.51
ALOX15 P16050 3/20 0.49
ALDH1A1 P00352 3/20 0.49
CYP1B1 Q16678 1/20 0.49
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.37
RAB9A P51151 1/20 0.36
CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8280195 1.00 TSHR (0.69) TSHRLMNATRPA1TRPV1ALOX15
SCHEMBL8591050 0.89 TSHR (0.71) TSHRLMNATRPA1TRPV1ALOX15
SCHEMBL818273 0.83 LMNA (0.46) TSHRLMNATRPV1ALDH1A1TP53
SCHEMBL13041969 0.83 LMNA (0.50) TSHRLMNATRPV1CHRM3
SCHEMBL28867133 0.83 TSHR (0.63) TSHRLMNATRPA1TRPV1ALOX15
SCHEMBL13301247 0.83 TSHR (0.77) TSHRLMNATRPA1TRPV1ALOX15
SCHEMBL14626987 0.83 TSHR (0.77) TSHRLMNATRPA1TRPV1ALOX15
SCHEMBL8591960 0.82 TSHR (0.71) TSHRLMNATRPA1TRPV1ALOX15
Perillic Acid SCHEMBL8434974 0.81 TSHR (1.00) TSHRLMNATRPA1TRPV1ALOX15
Perillic Acid SCHEMBL19341660 0.81 TSHR (1.00) TSHRLMNATRPA1TRPV1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250249108-A1 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2025-08-07 US claimed
EP-4504211-A2 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2025-02-12 EP claimed
WO-2023196668-A2 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2023-10-12 WO claimed
CN-104945336-B Perillic acid methyl esters nitrogen containing derivative and its preparation and application 沈阳药科大学 2018-02-16 CN claimed
EP-0750497-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1997-01-02 EP claimed
US-5470877-A Causing carcinoma regression WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-11-28 US claimed
WO-1995024895-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-09-21 WO claimed
US-20250249108-A1 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2025-08-07 US disclosed
EP-4504211-A2 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2025-02-12 EP disclosed
WO-2023196668-A2 PRODRUGS FOR CANCER TREATMENT GATC Health Corp (US) 2023-10-12 WO disclosed
CN-104945336-B Perillic acid methyl esters nitrogen containing derivative and its preparation and application 沈阳药科大学 2018-02-16 CN disclosed
US-20170260121-A1 COMPOUND, PROCESS FOR PREPARING A COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF A COMPOUND AND METHOD FOR TREATING CANCER FUNDAÇÃO OSWALDO CRUZ (BR) 2017-09-14 US disclosed
EP-3184503-A1 PERILLIC ACID DERIVATIVE, METHOD FOR PREPARING A PERILLIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION, USE OF A PERILLIC ACID DERIVATIVE AND CANCER TREATMENT METHOD Fundaçâo Oswaldo Cruz (BR) 2017-06-28 EP disclosed
EP-0750497-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1997-01-02 EP disclosed
US-5470877-A Causing carcinoma regression WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-11-28 US disclosed
US-5470877-A Causing carcinoma regression WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-11-28 US disclosed
US-5470877-A Causing carcinoma regression WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-11-28 US disclosed
WO-1995024895-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-09-21 WO disclosed
WO-1995024895-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-09-21 WO disclosed
WO-1995024895-A1 USES OF PERILLYL ALCOHOL AND PERILLIC ACID METHYL ESTER WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260121-A1 COMPOUND, PROCESS FOR PREPARING A COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF A COMPOUND AND METHOD FOR TREATING CANCER CA2, KCNMA1, KCNJ11 TSHR 4626/4885LMNA 1681/4885TRPA1 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.