Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324577 | 0.90 | LMNA (0.37) | LMNATSHRCHRM3CHRM2CHRM4 | |
| SCHEMBL13041969 | 0.86 | LMNA (0.50) | LMNATSHRCHRM3TRPV1CHRM2 | |
| SCHEMBL11331535 | 0.86 | TSHR (0.63) | LMNATSHRTRPV1CES2GABRR1 | |
| SCHEMBL8280195 | 0.83 | TSHR (0.69) | LMNATSHRCHRM3TRPV1TP53 | |
| SCHEMBL1810087 | 0.83 | TSHR (0.69) | LMNATSHRCHRM3TRPV1TP53 | |
| SCHEMBL28996156 | 0.79 | CHRM3 (0.40) | LMNATSHRCHRM3CHRM2CHRM4 | |
| SCHEMBL9816400 | 0.79 | LMNA (0.55) | LMNATSHRPTPN1BRD4TP53 | |
| SCHEMBL13041392 | 0.79 | CHRM3 (0.40) | LMNATSHRCHRM3CHRM2CHRM4 | |
| SCHEMBL15482109 | 0.79 | LMNA (0.55) | LMNATSHRPTPN1BRD4TP53 | |
| SCHEMBL10684675 | 0.77 | SMN1; SMN2 (0.39) | LMNATSHRBRD4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422612-B | Synthetic method of aromatic hydrocarbon compound | 中国科学院大连化学物理研究所 | 2021-08-10 | — | — | CN | disclosed |
| US-10913702-B2 | Method for cycloaddition of dimethyl muconate | SK CHEMICALS CO.. LTD. (KR) | 2021-02-09 | — | — | US | disclosed |
| US-20200399201-A1 | METHOD FOR CYCLOADDITION OF DIMETHYL MUCONATE | SK CHEMICALS CO., LTD. (KR) | 2020-12-24 | — | — | US | disclosed |
| CN-105384652-A | Process for preparing 2, 5-di (substituted) arylamino terephthalic acid | Lily group co ltd | 2016-03-09 | — | — | CN | disclosed |
| US-9018408-B2 | Processes for producing terephthalic acid and terephthalic esters | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| EP-2686293-A1 | PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND TEREPHTHALIC ESTERS | Dow Global Technologies LLC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-20130345467-A1 | PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND TEREPHTHALIC ESTERS | DOW GLOBAL TECHNOLOGIES LLC | 2013-12-26 | — | — | US | disclosed |
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| WO-2010148081-A2 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148081-A2 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148063-A2 | CYCLOHEXENE 1,4-CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148049-A2 | PREPARATION OF TRANS, TRANS MUCONIC ACID AND TRANS, TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148080-A2 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148080-A2 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148070-A2 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
| US-4255588-A | Synthesis of cyclohexene dicarboxylic acid esters | GULF OIL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399201-A1 | METHOD FOR CYCLOADDITION OF DIMETHYL MUCONATE | MUC1, MPST, DIMT1 | LMNA 4519/4885TSHR 1215/4885CHRM3 762/4885 |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | MUC1, FUT6, ST6GAL1 | LMNA 2726/4885TSHR 762/4885CHRM3 1357/4885 |
| US-10913702-B2 | Method for cycloaddition of dimethyl muconate | MUC1, MPST, DIMT1 | LMNA 4519/4885TSHR 1215/4885CHRM3 762/4885 |
| US-20130345467-A1 | PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND TEREPHTHALIC ESTERS | DDT, HDHD5, MCCC2 | LMNA 3104/4885TSHR 1817/4885CHRM3 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.