Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27629014 | 0.91 | GABRA2 (0.50) | CYP1A2TSHRMAPTALDH1A1NPC1 | |
| SCHEMBL27880448 | 0.83 | CHRNA4 (0.37) | CYP1A2ESR1ALDH1A1MEN1NPC1 | |
| SCHEMBL27571184 | 0.83 | TSHR (0.51) | CYP1A2TSHRMAPTESR1ALDH1A1 | |
| SCHEMBL25282733 | 0.82 | RAB9A (0.40) | CYP1A2TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL28232554 | 0.81 | ALDH1A1 (0.50) | CYP1A2TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL28861082 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTESR1ALDH1A1NPC1 | |
| SCHEMBL28228087 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTESR1ALDH1A1NPC1 | |
| SCHEMBL28227291 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTESR1ALDH1A1NPC1 | |
| SCHEMBL28227296 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTESR1ALDH1A1NPC1 | |
| SCHEMBL28228083 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTESR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955605-A | Hederagenin A cycloisoxazole-3-ethyl formate derivative and preparation method and application thereof | 烟台大学 | 2024-11-15 | — | — | CN | claimed |
| CN-105777661-B | 5‑（Substitute benzylideneamino）The preparation method of the acid ethyl ester derivatives of 4 substituted-phenyl isoxazole 3 | 沈阳药科大学 | 2018-01-02 | — | — | CN | claimed |
| CN-105777661-A | Preparation method of 5-(substituted benzimido)-4-substituted phenylisoxazole-3-carboxylic ethyl ester derivatives | 沈阳药科大学 | 2016-07-20 | — | — | CN | claimed |
| EP-3684773-B1 | THAILANSTATIN ANALOGS | PH PHARMA CO LTD (KR) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025096751-A1 | MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE | ESPERION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-118994142-A | Furanamide compound and application thereof | 浙江大学金华研究院 | 2024-11-22 | — | — | CN | disclosed |
| CN-118955605-A | Hederagenin A cycloisoxazole-3-ethyl formate derivative and preparation method and application thereof | 烟台大学 | 2024-11-15 | — | — | CN | disclosed |
| US-20240158385-A1 | NOVEL COMPOUNDS | Cerevance, Inc. | 2024-05-16 | — | — | US | disclosed |
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-111788208-B | Talarstatin analogues | PH制药有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | disclosed |
| US-5041567-A | Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis | BEECHAM GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-4812470-A | Antibacterial monic acid derivatives | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | disclosed |
| EP-0087953-B1 | ANTIBACTERIAL 1-NORMON-2-YL-HETEROCYCLIC COMPOUNDS | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |
| EP-0087953-A2 | Antibacterial 1-normon-2-yl-heterocyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158385-A1 | NOVEL COMPOUNDS | KCNK3, KCNA4, KCNK13 | CYP1A2 251/4885TSHR 2243/4885MAPT 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.