SCHEMBL18102776

SCHEMBL18102776

O=c1c(OS(=O)(=O)O)c(-c2ccc(OS(=O)(=O)O)c(OCOc3cc(OS(=O)(=O)O)cc4oc(-c5ccc(OS(=O)(=O)O)c(OS(=O)(=O)O)c5)c(OO)c(=O)c34)c2)oc2cc(OS(=O)(=O)O)cc(O)c12

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.71
F13A1 P00488 1/20 0.64
ELANE P08246 13/20 0.56
PLG P00747 6/20 0.55
ACE2 Q9BYF1 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18094962 0.85 F10 (0.86) F10F13A1ELANEPLG
SCHEMBL18094964 0.84 F10 (0.84) F10F13A1ELANEPLG
SCHEMBL18102775 0.84 ACE2 (0.58) ELANEPLGACE2
SCHEMBL5072262 0.82 F10 (0.72) F10F13A1PLGACE2
SCHEMBL18102777 0.82 F10 (0.79) F10F13A1ELANEPLGACE2
SCHEMBL8015255 0.75 TUBB4A (0.67) F10ELANE
SCHEMBL6122217 0.74 ACE2 (0.59) F10F13A1ELANEPLGACE2
SCHEMBL3642770 0.73 TUBB4A (0.69) F10
SCHEMBL19749974 0.72 ACE2 (0.72) PLGACE2
SCHEMBL18102797 0.72 ACE2 (0.58) PLGACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280676-A1 SULFATED AND UNSULFATED FLAVONOID OLIGOMERS AS CANCER THERAPEUTICS VIRGINIA COMMONWEALTH UNIVERSITY 2016-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280676-A1 SULFATED AND UNSULFATED FLAVONOID OLIGOMERS AS CANCER THERAPEUTICS CD44, UGGT1, TSG101 F10 745/4885F13A1 1381/4885ELANE 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.