Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21836283 | 0.85 | ALDH1A1 (0.42) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL1810308 | 0.83 | HCAR2 (0.61) | HCAR2KDM4EFFAR2PRKAB2PRKAG1 | |
| SCHEMBL21448921 | 0.83 | FFAR2 (0.43) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL5196234 | 0.83 | FFAR2 (0.40) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL21244224 | 0.81 | CDC7 (0.41) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| Hydrochloric Acid SCHEMBL11597191 | 0.81 | HCAR2 (0.59) | HCAR2KDM4EFFAR2PRKAB2PRKAG1 | |
| SCHEMBL1107386 | 0.78 | HCAR2 (0.68) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL472995 | 0.78 | CSNK2A2 (0.42) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL4292895 | 0.78 | HCAR2 (0.42) | HCAR2KDM4EMAPK1L3MBTL1FFAR2 | |
| SCHEMBL17204603 | 0.78 | HCAR2 (0.50) | HCAR2KDM4ELMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564239-B9 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN INC (US) | 2023-04-19 | — | — | EP | disclosed |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| EP-3564239-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | Shenzhen Immunova Pharmaceutical Co., Ltd. (CN) | 2019-11-06 | — | — | EP | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | MIIKANA THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| US-7345043-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS (US) | 2008-03-18 | — | — | US | disclosed |
| US-7345043-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS (US) | 2008-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | HCAR2 15/4885KDM4E 2566/4885MAPK1 2104/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | HCAR2 14/4885KDM4E 2197/4885MAPK1 2641/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | HCAR2 14/4885KDM4E 2197/4885MAPK1 2641/4885 |
| US-20080139535-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC10 | HCAR2 1963/4885KDM4E 764/4885MAPK1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.